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Sub-Topics Nanotechnology Robotics Stem Cells Also Try Biochemistry Genetics Microbiology Neuroscience Books -Genomes - To Know Ourselves (US Department of Energy and the Human Genome Project) Provides information on recent research to sequence human genomes. 9-05 Lesson Plans Adaptation and Evolution Lesson (British Columbia Ministry of Education) Provides a lesson on adaptation and evolution for the 11th grade level. The materials are called an Integrated Resource Package. 2-01 Lists Cells (Awesome Library) Provides information on genes, cells, chromosomes, DNA, and more. 2-02 Cells - Dictionary of Cell Biology (Virtual Library of Biochemistry and Cell Biology - Fenteany) Provides explanations of basic cell structure and activity at an advanced high school or beginning college level. 2-01 Chromosomes (Awesome Library) Provides information on genes, cells, chromosomes, DNA, and more. 2-02 DNA (Awesome Library) Provides information on genes, cells, chromosomes, DNA, and more. 2-02 Genetics (Awesome Library) Provides information on genes, cells, chromosomes, DNA, and more. 2-02 Materials -Spelling Checkers for Biotechnology (Awesome Library) Checks online for correct spelling and offers alternatives if the spelling is incorrect. Also offers glossaries for browsing terms. 7-02 News -06-10-06 New Robotic Arm Directed by Thoughts (BBC News) "Scientists in the US have created a robotic arm that can be controlled by thought alone." 06-06 -10-30-05 "Brain Work" to Make Games More Realistic (MSNBC News) "Just imagine being rendered the rough equivalent of a radio-controlled toy car." "Nippon Telegraph & Telephone Corp., Japans top telephone company, says it is developing the technology to perhaps make video games more realistic. But more sinister applications also come to mind." 10-05 -11-03-04 California to Fund Stem Cell Research (ABC News) "Californians voted Tuesday to spend $3 billion on stem cell research, putting the state on the cutting edge of a field questioned by conservatives and the Bush administration. Arizonans approved a crackdown on illegal immigrants, adopting a measure that would deter them from voting or obtaining certain government services." 11-04 -11-04-04 Nicotene Gene Discovered (Independent) "A single gene could be responsible for determining how easily people become addicted to smoking, according to a report published today." 11-04 -11-14-04 Company Gives Away Stem Cell Line (China View) "An Australian biotech company announced Monday that it is to release the embryonic stem cell line it has developed to world researchers for free." "The Stem Cell Sciences Ltd. (SCS) made the announcement when opening a new laboratory at Monash University's Clayton Campus in Melbourne, capital of Victoria state." 11-04 -11-23-07 Yellowstone Park's Extremophile Microbes (Time.com) "Yellowstone Park's bizarre steam vents and odiferous boiling pools are more than just tourist attractions and geological curiosities. They are home to unique microbes — living organisms that thrive in extreme heat. More than that, they are valuable resources for industries searching for fresh and big profits." 11-07 Biotechnology News (Yahoo) Provides top news stories related to biotechnology and genetics research. 11-01. Genome Mapping - Ethics (Macmillan Publishers - Nature) Provides news on the ethical debates and policies that are arising out of genome mapping. 6-00 Genome Mapping News - Non-Human (Macmillan Publishers - Nature) Provides the latest news, as well as past news stories, on mapping the non-human genomes. 6-00 Science News (Nature.com) Provides refereed articles. 8-05 Papers -Cloning - The Process (Roslin Institute) Provides information on the breakthrough scientific discovery by the group that succeeded. Bateson, William (BBC History) "Initial research into worms led Bateson to invent the language and discipline of genetics." 5-02 Bioinformatics Definitions and History (Bioinformatics) " 'The mathematical, statistical and computing methods that aim to solve biological problems using DNA and amino acid sequences and related information.' " 1-04 Biomimicry (Time.com - Amory B. Lovins) "[Janine] Benyus draws her design inspiration from nature's wisdom, not people's cleverness. Some 3.8 billion years of evolution have exposed the design flaws of roughly 99% of nature's creations — all recalled by the Manufacturer. The 1% that have survived can teach powerful lessons about how things should be built if they're to last. For example, nature's design genius has led to the creation of bat-inspired ultrasonic canes for the blind, synthetic sheets that collect water from mist and fog as desert beetles do, and paint that self-cleans like a lotus leaf. Little plastic-film patches have been designed using adhesiveless gecko-foot technology, so that carpet tiles can be stored in a big roll, but also easily removed. Equally promising, we'll soon make solar cells like leaves, supertough ceramics that resemble the inner shells of abalone, and underwater glue that mimics the natural as forests." 10-07 Body Clock - Chronobiology (G.D. Searle Corp) Describes chronobiology and chronotherapeutics, the study of different effects of medications and other therapeutics at different times of day and night. 5-01 Brain - Compound Fights Prion Brain Disease (applesforhealth) The Nobel laureate who discovered that certain degenerative brain diseases were caused by substances called prions says he has found a promising compound that appears to clear away the infectious proteins in laboratory tests. 12-17-99. Brain Region Mapped (applesforhealth) Researchers have mapped a region of the brain responsible for a certain kind of multitasking behavior that is uniquely human. 10-22-99. Cancer - Repairing DNA After UV Damage (applesforhealth) Texas researchers have identified a gene responsible for some cases of a pigment abnormality that raises the risk of skin cancer by 1,000 times. 07-16-99. Cancer - Unmasking Genetic Causes Of Cancer (applesforhealth) Researchers playing peek-a-boo with mutant genes that increase the risk of colon cancer have determined a way to unmask the troublemakers nearly 100 percent of the time. 02-25-00. Cell Transplant Fixes Damaged Brain (applesforhealth) An experimental technique that stopped shivering in mice may lead to new treatments for multiple sclerosis, paralysis, Alzheimer's disease and other brain wasting disorders. 06-18-99. Chemistry Nobel Laureates - Biochemistry (Nobel Foundation) Provides short autobiographies of the Nobel laureates Paul Berg, Walter Gilbert, and Frederick Sanger for their seminal work with nucleic acids and recombinant DNA. Their work has formed a foundation for modern biochemistry. 9-00 Cloning - The Process (CNN - Kellan) Provides information on the process of cloning used in the breakthrough scientific discovery. Cloning Genes (BIO) Describes and illustrates how cloning is performed. Cloning Techniques and Debate (ThinkQuest.org 24355 and Kayotic Development) Provides details of different techniquest of cloning, as well as ethical issues, misconceptions, and a questionnaire. 5-02 Cloning and Bioethics (CNN) President Bill Clinton asks bioethics commission to look at sheep cloning. Provides links on bioethics related to cloning. Cloning and Bioethics (Center for Bioethics) Presents a forum for discussing ethical issues related to biological research. Cloning and Bioethics (US Department of Energy and the Human Genome Project) Discusses ethical, legal, and social implications of genetic research. Cloning and Bioethics - An Interview (Ross) Presents an interview with Dr. Ian Wilmut, the person who first succeeded in cloning a mammal. Designer Enzymes Developed (applesforhealth) In a feat with major implications for the pharmaceutical and biotechnology industries, researchers have devised a way to design novel enzymes, key proteins that speed up chemical reactions in a cell. 02-25-00. Eat Your Tortillas, You Need The Iron (applesforhealth) A new variety of corn, patented by the U.S. Department of Agriculture in 1997, may prove a boon to Latin Americans -- and others -- with iron-deficiency anemia. 03-24-00. Editorial - Christopher Reeve Enboldened Many of Us (MSNBC.com) "People who never met Christopher Reeve were emboldened by his crusade." 10-04 Ethical, Legal, and Social Implications of Human Genetics Research (ELSI) Provides articles and a history of ELSI. 2-01 Ethics - Bioethics Resources (National Institutes of Health) Provides articles and organizations addressing bioethics as it relates to biotechnology. 2-01 Ethics and Character Development (Mining Co. - Walker) Provides links to articles and lessons related to ethics and character development. Farmers Suspicious Of Modified Crops (applesforhealth) Opposition to the use of genetically modified crops in food supplies seems to be having an effect on U.S. farmers. 12-24-99. Gene Alters Social Behavior (applesforhealth) Emory University researchers have found a single gene that appears to influence pair bonding and monogamy, at least in rodents, providing a clue that may lead to treatments for social human disorders such as autism. 08-20-99. Gene Crucial To Paralysis Found (applesforhealth) Scientists have discovered a long-sought gene that prevents the regeneration of damaged nerve cells, leaving some victims of stroke, neurodegenerative disorders, traffic accidents and athletic mishaps forever unable to move. 02-04-00. Gene Lets You See Speedy Objects (applesforhealth) Scientists studying mice have identified a gene that lets you see a baseball flying at 90 miles per hour. 02-18-00. Gene Maps (applesforhealth) Triumphant from their decoding of complete genetic blueprints of living organisms, scientists are now intent on an even more daunting task - finding out what all those newly revealed genes do and how what they do can be put to good use. 11-26-99. Gene Repair Adds Pigment To Hair (applesforhealth) Researchers are reporting they've repaired hair pigment genes, making albino mice produce a few black hairs. 01-14-00. Genes and Disease (National Center for Biotechnology Information) Provides an introduction to the importance of sequencing the human gene for preventing future diseases. Includes a colorful photograph of a complete set of human genes from a leukemia patient. 2-02 Genes and Miniaturization - Beyond Biology (US Department of Energy and the Human Genome Project) Describes how information from genes applies to miniaturization and helping humans. Genetic Disorder Therapy Likely (Ryan Foundation) "The idea of using enzyme replacement therapy for genetic diseases such as Hurler/Scheie has been around for a long time, 'but we despaired of ever going to clinical trials because it costs a lot of money,' said Neufeld, who discovered the mutated gene that causes MPS-1." The parents of a child with the genetic disorder put together a foundation and raised over $1 million for research. An effective therapy seems to have been found as a direct result of their funding efforts. "Children with the disorder - about one in every 25,000 born in the United States - are missing an enzyme called alpha-L-iduronidase that breaks down mucopolysaccharides." 6-02 Genetically Modified Monkey (National Geographic Society) Provides news on a rhesus monkey that was given a genetic marker during fertilization. Scientists believe that the procedure can be used to introduce medical conditions, such as diabetes, into monkeys in order to speed research efforts for cures for humans. 1-01 Genome - Implications of Research (New Scientist) Discusses what may happen as a result of key discoveries in biotechnology, especially genome research. 8-00. Genome Decoded of Meningitis Bacteria (applesforhealth) Scientists decoded the genome of a bacterium that causes deadly meningitis epidemics, a feat that researchers say could lead to solutions to intractable infectious diseases. 04-07-00. Genome Sequence of Rice Completed (Myriad) Provides an explanation of genome research and why it is important. The research is intended to form a basis for improving the yield and healthiness of rice. 1-01 Hemoglobin - Secrets Of Hemoglobin Revealed (applesforhealth) Researchers studying an intestinal parasite have found out some important secrets of hemoglobin. 10-15-99. Lewis, Edward B. (BBC History) Provides a short biography of the Nobel Prize winner for his work in genetics. 5-02 Life May Originate in Space (CNN) Provides results of a study that indicates that cell-like membranes "self-assemble" in space and could be precursors for the development of life. 1-01 Microbes May Be Most Plentiful (PBS) Provides a description of the microbe Sar 11, recently discovered by Dr. Steven Giovannoni, that may be the most abundant life form on earth. It is also one of the smallest microbes ever discovered and one of the hardest to grow in the lab. 1-01 More Research On Genetically Engineered Food (applesforhealth) Genetically engineered food may be needed to help feed the growing nutrition needs in developing countries, but in the United States scientists are urging more studies be done to determine the environmental effects of these foods. 03-03-00. Pain Reduced with Brain Electrons (San Francisco Chronicle - Hall) Describes a new therapy for intractable pain. 5-02 Photographic Techniques - Microscopic (SciencePhoto.com) Provides color pictures of microscopic objects and describes how it is done. 8-01 Remote Control of Rats (Washington Post) Shows a diagram of a rat that can be controlled remotely. 5-02 Researchers Disarm Salmonella Germ (applesforhealth) California germ experts say they have found the genetic Achilles heel of the food poisoning bug salmonella, a discovery that could lead to powerful replacements for the current crop of antibiotics losing their punch against disease-causing microbes. 06-25-99. Ribosome - Complete Ribosome Imaged (applesforhealth) The ribosome is a molecular machine fundamental to all life. 10-22-99. Safety Checks In Nervous System (applesforhealth) Investigators have discovered a safety-check mechanism that ensures proper wiring of the nervous system. 10-29-99. Scientists Synthesize Potent Antibiotic (applesforhealth) Scientists developed an artificial version of a potent antibiotic that appears to thwart several bacterial strains, including two resistant to current treatments. 04-14-00. Search GeneBank, Genomes, Proteins, and Structures (National Center for Biotechnology Information) "Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease." 2-02 Search GeneBank, Genomes, Proteins, and Structures (National Center for Biotechnology Information) "Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease." 2-02 Super Computers From Living Cells (applesforhealth) Researchers are announcing they caused single molecules to produce the most basic element of computer function, making possible the development of computers a billion times faster than the most powerful PCs. 07-23-99. Tuberculosis Gene Identified (applesforhealth) Researchers have identified a gene necessary for the tuberculosis bacterium to wreak its disease-causing havoc in the lung. 01-14-00. Venter, J. Craig - Science Man of the Year (Time.com) Describes Venter's achievements in gene research to make him, according to Time magazine, one of the great pioneers of the 21st century. 12-00 Periodicals Cell Biology (Cell Press) Provides research results in cell biology. College Level. 5-01 Development (The Company of Biologists, LTD) "Development is a primary research journal providing an insight into mechanisms of plant and animal development, covering all aspects from molecular and cellular to tissue levels." Provides full text of issues back to 1992. Does not include full text of current issue. College Level. 5-01 Journal of Cell Science (The Company of Biologists, LTD) Provides full text of issues back to 1992. Does not include full text of current issue. College Level. 5-01 Journal of Experimental Biology (The Company of Biologists, LTD) Provides full text of issues back to 1992. Does not include full text of current issue. College level. 12-02 New Scientist (Planet Science) Provides a bridge to the latest interesting research. Projects Extremophiles (NASA Science) Provides articles, lessons, and worksheets related to life forms that can thrive in very extreme conditions, such as heat, cold, pressure, radiation, salt, and even the vacuum of space. 8-00 Genentech's Biotech Projects Research New Antibiotics Successful Against Superbugs (Scientific American) "Doctors first identified methicillin-resistant Staphylococcus aureus (MRSA) bacteria in the 1960s and hospitals have been fighting to control their spread ever since. MRSA carry a unique protein called PBP 2a on the cell membrane that plays a key role in helping to defend against antibiotics. In February, Shahriar Mobashery of Notre Dame University and his colleagues identified specific components of the bacterial cell wall that interact with PBP 2a to form a chemical barricade. The team has now made three new synthetic antibiotics based on cephalosporin, a close relative of penicillin. The compounds contain protein components that mimic the crucial parts of the cell wall that cooperate with PBP 2a, which leads to its deactivation and forces the bacterium to succumb to the medication." 9-05

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