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News -02-18-08 A Thousand Lives a Month Lost (CBS News) "How much did Bayer know? And why did it take Bayer and the U.S. Food and Drug Administration nearly two years to take the drug off the market after major studies revealed the danger? Two years - during which it's estimated Trasylol was contributing to the loss of one thousand lives a month." 02-08 Papers Drug Cuts Deaths After Heart Attacks (Scientific American) "Taking a blood-thinning drug in addition to aspirin daily after a heart attack significantly reduced the risk of death, follow-up heart attacks and strokes, according to a six-year study of nearly 46,000 patients in China. Researchers found that the drug, clopidogrel, increased overall survival by 9 percent." 12-05 Heart Pill Could Save Millions (CBS News) "A three-in-one pill being developed to treat heart disease could save millions, particularly in developing countries where most heart attacks occur, experts said Monday at the World Congress of Cardiology." 09-06 New System Reduces Wait in Heart Attacks (ABC News) "If time spent transporting a suspected heart attack victim to a hospital could be used to work out a diagnosis and treatment plan, doctors say, more lives could be saved and now that will be possible in central Arkansas." 12-06 Study: Angioplasties Needed Within 90 Minutes of a Heart Attacks (PBS News) "Two major findings presented at an American Heart Association meeting in Chicago this week could make a difference in how heart attack patients are treated." "Opening clogged arteries by balloon angioplasty is still the recommended response, but only one-third of heart attack victims get them as quickly as they should, within 90 minutes of their arrival at the hospital. And getting an angioplasty more than three days after a heart attack does not reduce the risk of having another one." 03-07 Research -09-01-08 Study: Regime As Effective As Statins (MSNBC News) "A regimen of supplements and lifestyle coaching is just as effective as statin medication for reducing levels of low-density lipoprotein (LDL) or "bad" cholesterol, and more effective in helping people lose weight, new research shows." 09-08 Higher Doses of Statin Drugs Yield Excellent Results (iVillage.com) "The 'miracle' cholesterol-lowering drugs called statins have just become more miraculous." "New research shows high levels of the drugs given to people who have just been hospitalized with heart attacks or high-risk unstable angina not only prevented future 'events' but also saved lives." "These findings call into question current guidelines on how low low-density lipoprotein (LDL, or the 'bad' cholesterol) levels should be." "But even today, as the editorial points out, only about 11 million people are getting statins when an estimated 36 million should be on them. Worldwide, more than 200 million people meet the criteria for treatment with statins while only 25 million are actually taking the drugs." "This is largely a cost issue, Topol states. His editorial points out that in Cleveland, the cost of 10 mg of atorvastatin per day (the recommended starting dose) is $900 per year, while the 80-mg dose costs $1,400 per year. At a collective $12.5 billion, statins are the largest prescription drug expenditure in the United States, he writes." 3-04 Higher Doses of Statin Drugs Yield Excellent Results (iVillage.com) "The 'miracle' cholesterol-lowering drugs called statins have just become more miraculous." "New research shows high levels of the drugs given to people who have just been hospitalized with heart attacks or high-risk unstable angina not only prevented future 'events' but also saved lives." "These findings call into question current guidelines on how low low-density lipoprotein (LDL, or the 'bad' cholesterol) levels should be." "But even today, as the editorial points out, only about 11 million people are getting statins when an estimated 36 million should be on them. Worldwide, more than 200 million people meet the criteria for treatment with statins while only 25 million are actually taking the drugs." "This is largely a cost issue, Topol states. His editorial points out that in Cleveland, the cost of 10 mg of atorvastatin per day (the recommended starting dose) is $900 per year, while the 80-mg dose costs $1,400 per year. At a collective $12.5 billion, statins are the largest prescription drug expenditure in the United States, he writes." 3-04

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