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Papers Heart Pill Could Save Millions (CBS News) "A three-in-one pill being developed to treat heart disease could save millions, particularly in developing countries where most heart attacks occur, experts said Monday at the World Congress of Cardiology." 09-06 New Heart Attack Tests Recommended (CBS News) "It's time to change the way doctors predict heart attacks and stroke, says a group of prominent cardiologists. They call for routine use of CT scans to directly measure artery-clogging plaque, or ultrasounds to directly measure narrowing of the arteries." According to Naghavi, " 'For the very first time in heart medicine, we now have a test that can show someone has up to a 65-fold increased risk of a heart attack,' he says. 'With the traditional risk factors, the biggest risk is high cholesterol, which has only up to 4.5-fold increased risk. So you can see how much of a jump in prediction we get from this.' ” 07-06 Study: 27,000 Heart Attacks Associated Vioxx (USA Today) "The study, an analysis of a database of 1.4 million Kaiser Permanente members, found that those who took Vioxx were more likely to suffer a heart attack or sudden cardiac death than those who took Celebrex, Vioxx's main rival. Based on their findings, Graham and his collaborators linked Vioxx to more than 27,000 heart attacks or sudden cardiac deaths nationwide from the time it came on the market in 1999 through 2003." 11-04 Worst Trans Fat Foods (MSNBC Health News) "According to a report published in April by researchers at the Harvard School of Public Health and Wageningen University, eliminating trans fats from the U.S. food supply could prevent between 6 percent and 19 percent of heart attacks and related deaths each year." "Saturated fats raise the bad cholesterol, or LDL, and the good, HDL, but trans fats perform the double whammy of raising bad and lowering good cholesterol. Bad cholesterol causes plaque to build up in and eventually clog arteries." 01-07 Research C-Reactive Protein to Diagnose Heart Attack Risk (P-S-L Consulting Group) Provides information on a new method of assessing risk for heart attacks. 10-00 Higher Doses of Statin Drugs Yield Excellent Results (iVillage.com) "The 'miracle' cholesterol-lowering drugs called statins have just become more miraculous." "New research shows high levels of the drugs given to people who have just been hospitalized with heart attacks or high-risk unstable angina not only prevented future 'events' but also saved lives." "These findings call into question current guidelines on how low low-density lipoprotein (LDL, or the 'bad' cholesterol) levels should be." "But even today, as the editorial points out, only about 11 million people are getting statins when an estimated 36 million should be on them. Worldwide, more than 200 million people meet the criteria for treatment with statins while only 25 million are actually taking the drugs." "This is largely a cost issue, Topol states. His editorial points out that in Cleveland, the cost of 10 mg of atorvastatin per day (the recommended starting dose) is $900 per year, while the 80-mg dose costs $1,400 per year. At a collective $12.5 billion, statins are the largest prescription drug expenditure in the United States, he writes." 3-04

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