Terms: alzheimer
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- -12-08-05 Protein p25 Associated with Alzheimer's Disease -- and Creativity (HHMI.org)
" Researchers have found evidence that may partially exonerate a protein known to be a culprit in the progression of Alzheimer's disease. Their new studies show that the protein p25, which wreaks havoc in the brains of patients with Alzheimer's disease, also has a good side in promoting the plasticity of the brain." 12-05.
- -12-08-05 Protein p25 Associated with Alzheimer's Disease -- and Creativity (HHMI.org)
" Researchers have found evidence that may partially exonerate a protein known to be a culprit in the progression of Alzheimer's disease. Their new studies show that the protein p25, which wreaks havoc in the brains of patients with Alzheimer's disease, also has a good side in promoting the plasticity of the brain." 12-05.
- -12-11-05 Compound in Some Foods Attack Alzheimer's Agent (Scientific American)
 " 'Resveratrol is a natural polyphenol occurring in abundance in several plants, including grapes, berries and peanuts,' says author Philippe Marambaud of the Litwin-Zucker Research Center for the Study of Alzheimer's Disease and Memory Disorders in Manhasset, N.Y. 'The polyphenol is found in high concentrations in red wines.' "
"The scientists found that 40 micromoles (a measure of the amount of resveratrol in a liter of solution) cut levels of the Alzheimer's-associated molecules--amyloid-beta peptides--by more than half." 9-03
- -06-15-06 Alzheimer's Vaccine Shows Promise (ABC News)
"An experimental vaccine is showing promise against Alzheimer's disease, reducing brain deposits that are blamed for the disorder." 06-06
- Alzheimer's Disease - Memory Loss in Mice Reversed (Scientific American)
More than four million Americans currently suffer from Alzheimer's disease and the number is expected to balloon as the population ages. The results of a new mouse study offer fresh hope that the damage inflicted by the disease could be at least partially reversible."
"In humans, two different substances that accumulate in the brain are implicated in Alzheimer's: twisted neurofibrillary tangles, which include tau proteins, and amyloid deposits comprised of toxic plaque build-up. For the study mice, after the mutant tau gene was dampened and some memory regained, their neuron numbers stabilized but the tangles remained. The tangles themselves may therefore not be responsible for causing memory problems, at least in mice." 7-05
- 01-14-07 Gene Linked to Alzheimer's Disease (MSNBC New)
"A huge international study has identified a gene that apparently can raise the risk of developing the most common form of Alzheimer's disease, a discovery that may help scientists develop new treatments." 01-07
- Alzheimer's Rate Increases (CBS News)
"More than 5 million Americans are living with Alzheimer's disease, a 10 percent increase since the last Alzheimer's Association estimate five years ago — and a count that supports the long-forecast dementia epidemic as the population grays." 03-07
- -05-13-07 Scientists Are Researching If Fish Oil Helps Alzheimer's patients (ScienceDaily.com)
"U.S.researchers are developing a clinical trial to see if omega-3 fatty acid slows the progression of Alzheimer's disease." 05-07
- Can Alzheimer's Be Prevented? (Time.com)
"Few things are as terrifying as losing one's mind. Alzheimer's disease is the most common form of dementia among the elderly and affects as many as 4.5 million Americans, according to the U.S. National Institutes of Health. It currently has no cure. But recent research offers groundbreaking insight into what causes the disease, and how researchers could reduce people's risk." 05-08
- -06-23-08 New Clue to the Cause of Alzheimer's Disease (Time.com)
"Now, researchers have caused Alzheimer's symptoms in rats by injecting them with one particular form of beta-amyloid. Injections with other forms of beta-amyloid did not cause illness, which may explain why some people have beta-amyloid plaque in their brains but do not show disease symptoms." 06-08
- -07-28-08 Statins May Reduce Risk of Alzheimer's Disease (Newsweek)
"A study appearing Monday in the journal Neurology found that statins dramatically reduced the risk of developing dementia and Alzheimer's disease among a group of subjects 60 years and older. 'It suggests that if you took statins before dementia set in, you might be 50% less likely to develop the condition,' says Mary Haan, an epidemiology professor at the University of Michigan and the study's lead author. 'That's a really big effect.' " 07-08
- -07-29-08 Study: Pre-Alzheimer's Hits Males Hard (MSNBC News)
 "A milder type of mental decline that often precedes Alzheimer’s disease is alarmingly more common than has been believed, and in men more than women, doctors reported Monday."
"Dr. Ralph Nixon, a New York University psychiatrist and scientific adviser to the Alzheimer’s Association, was blunt."
" 'We’re facing a crisis,' he said."
" 'There are no treatments now to prevent this mental slide or reverse it once it starts.' 07-08
- 07-29-08 New Alzheimer's Drug Shows Promise (CBS News)
"For the first time, an experimental drug shows promise for halting the progression of Alzheimer's disease by taking a new approach: breaking up the protein tangles that clog victims' brains."
"The encouraging results from the drug called Rember, reported Tuesday at a medical conference in Chicago, electrified a field battered by recent setbacks. The drug was developed by Singapore-based TauRx Therapeutics." 07-08
- -05-14-09 New Test to Predict Alzheimer's Disease (Time.com)
"Researchers at the University of California, San Francisco (UCSF), and the University of Pittsburgh have developed the first screening tool that can help predict whether elderly patients are at low, moderate or high risk of developing dementia. The new test takes into account characteristic risk factors for dementia, including advanced age and the presence of genes associated with Alzheimer's, but also relies on lesser-known contributors such as patients' body weight and alcohol-drinking habits." 05-09
- -09-06-09 Twenty Percent Fewer May Get Alzheimer's (MSNBC News)
"Scientists have found three new major genetic links to Alzheimer's, affecting up to 20 percent of people with the brain-wasting disease, and said on Sunday it was the most significant such discovery in 15 years." 09-09
- How to Protect Against Alzheimer's Disease (U.S. News)
"We all want to dodge the Alzheimer's bullet. And lucky us, Mother Nature has counterbalanced the power of our hard-wired genes by allowing multiple lifestyle choices to greatly influence our aging. Read: Your destiny is not fated; you do have some control." 09-09
- Alzheimer's Disease Research (Alzheimer Research Forum)
Provides news on Alzheimer's Disease. 7-04
- Alzheimer's Disease - Alzheimer's Association
- Alzheimer's Disease - Research on Alzheimer's Disease and Diet (Fisher)
Provides recommendations to combat Alzheimer's Disease through diet.
- Alzheimer's Disease (National Library of Medicine - Medline Plus)
Provides information on diagnosis and treatment. 11-99
- Alzheimer's Disease (About.com - Creason)
Provides information on diagnosis and treatment. Also provides information on top nursing homes, by state. 2-01
- Alzheimer's Research May Delay Effects (CBSNews.com)
Summarizes research on a human to see if injection of a genetically engineered nerve growth factor will delay the effects of Alzheimer's Disease. 2-01
- Alzheimer's Disease Research (National Center for Biotechnology Information)
Provides a summary of gene research related to preventing Alzhimer's disease. "Recently, use of a mouse model of the disease identified an enzyme that may be responsible for the increase in amyloid production characteristic of AD. If a way to regulate this enzyme could be found, then AD may be slowed or halted in some people." 2-02
- Alzheimer's Disease (Awesome Library)
- Cure for Early Alzheimer's in Mice (Scientific American)
"Alzheimer's disease is characterized by two separate brain lesions: plaques and tangles. The results of a new mouse study indicate that an experimental immune therapy that targets the former can also impact the latter, so long as the disease has not progressed to an advanced state." 8-04
- 11-12-04 New Compound May Slow Alzheimer's Disease (Scientific American)
"Now, borrowing a trick from soil bacteria, researchers have designed a small molecule that effectively forms a new drug on the spot by teaming up with a large protein that is common inside cells. As reported today in Science, the resulting complex binds to fragments of beta-amyloid protein and keeps them from sticking together to form the 'plaques' that are a hallmark of Alzheimer's disease." 8-04
- Alzheimer's Disease (Wikipedia.org)
"Alzheimer's disease (AD), a neurodegenerative disorder, is the most common cause of dementia and characterised clinically by progressive intellectual deterioration together with declining activities of daily living and neuropsychiatric symptoms or behavioral changes. The most striking early symptom is memory loss (amnesia), usually manifest as minor forgetfulness that becomes steadily more dense with illness progression, with relative preservation of older memories." 8-05
- -02-06-06 Study: Up to 79% of Late-Onset Alzheimer's is Genetic (USA Today)
"Genes account for 58% to 79% of a person's risk of developing late-onset Alzheimer's, a study reports today. It's the largest genetic study of Alzheimer's ever." 02-06
- -06-26-06 New Test for Alzheimer's Disease (CBS News)
"A new test may help scientists answer a perplexing 'which came first' question about the development of Alzheimer's disease, possibly pointing the way to earlier diagnosis or even treatment."
" 'The paper describes an extremely interesting and potentially important advance,' said Dr. Samuel Gandy of Thomas Jefferson University in Philadelphia said. 'This method is light-years ahead of any existing technology for approaching the issue,' said Gandy, who was not part of the research team." 06-06
- -07-22-06 Early Detection of Alzheimer's Soon Possible (BBC News)
"Early dementia could be detected with a simple eye test, similar to those used to test for high blood pressure and diabetes, US scientists believe."
"The scientists believe the technology, known as quasi-elastic light scattering, may detect the very earliest stages of amyloid deposits in the lens, even when they appear completely clear to the naked eye." 07-06
- -10-11-06 Alzheimer's Drugs Very Risky (Hosted.ap.org)
"Widely prescribed anti-psychotic drugs do not help most Alzheimer's patients with delusions and aggression and are not worth the risk of sudden death and other side effects, the first major study on sufferers outside nursing homes concludes." 10-06
- -01-12-07 Research: Folic Acid May Prevent Alzheimer's (US News)
"Here's another plug for broccoli and leafy green vegetables: The folic acid they contain may help reduce your risk of developing Alzheimer's disease." 01-07
- Alzheimer's Disease (Alz.org)
Provides news, articles, research, and information on diagnosis and prevention. 03-08
- Alzheimer's Disease and Kids (Alz.org)
"More than a quarter million American children age 8 to 18 are currently caring for loved ones with Alzheimer's. The fictional film my name is lisa depicts the struggles of a 13-year-old girl dealing with her mother's Alzheimer's." 03-08
- Human Cloning Advanced for Treating Disease (BBC News)
"South Korean scientists have cloned 30 human embryos to obtain cells they hope could one day be used to treat disease."
"The resulting embryos were then grown up to produce so-called stem cells that can divide into any tissue in the body."
"The aim is to use the cells to replace ones that have failed in patients with problems such as Alzheimer's disease." 2-4.
- 06-03-04 Reagan - Former President Ronald Reagan Dies (Bloomberg.com)
"Former U.S. President Ronald Reagan, who championed shrinking government at home and ending communism abroad, died after a lengthy struggle with Alzheimer's disease. He was 93."
"Reagan came to politics after a career as a movie actor and went on to become one of the most popular U.S. leaders of the 20th century. He served two terms as California's governor and two terms as the 40th U.S. president, winning re-election in 1984 with majorities in 49 of 50 states and the most electoral votes ever tallied." 6-04
- Arguments For and Against Stem Cell Research (BBC News)
"Opponents - led by the president himself - make the case that public money should not be used to support what they call the further destruction of human life."
"But supporters argue that such stem cell research could save lives, by providing treatment and even cures for diseases like Parkinson's, Alzheimer's, or childhood diabetes." 7-05
- Regular Exercise Can Reduce Risk of Dementia (MSNBC News)
"Older people who exercise three or more times a week are less likely to develop Alzheimer’s and other types of dementia, according to a study that adds to the evidence that staying active can help keep the mind sharp."
"Researchers found that healthy people who reported exercising regularly had a 30 to 40 percent lower risk of dementia."
- -02-17-06 Growing New Cells to Cure Neurological Diseases (ABC News)
"Scientists are getting closer to reaching one of the Holy Grails of medical research — regenerating brain cells to wipe out a wide range of neurological diseases, including Alzheimer's, Parkinson's and epilepsy." 02-06
- -03-14-06 Protein Complex in Brain Found to Cause Memory Loss (ABC News)
"Scientists have identified a substance in the brains of mice that causes memory loss, which could be a target for drugs to treat patients with Alzheimer's disease."
" 'Finding the specific cause of memory loss and cognitive decline gives scientists a protein complex to target,' said Professor Karen Ashe of the University of Minnesota Medical School in Minneapolis, who headed the research team." 03-06
- New Blood Test May Be 100,000 Times More Sensitive (ABC News)
"FACTT, shorthand for fluorescent amplification catalyzed by T7-polymerase technique, detects unusual proteins in the blood — sometimes the first telltale signal that something is wrong."
"If FACTT can find traces of unusual proteins or other molecules in the bloodstream, that might ultimately make it possible to pick up signs of Alzheimer's disease before it creates brain damage. It might pick up the errant proteins created by the human form of mad cow disease. It might also make it possible to find a cancer before a tumor shows up on a mammogram or other X-ray." 03-06
- -07-19-06 Bush Vetoes Stem Cell Research (ITV.com)
"US President George W Bush has blocked legislation to expand embryonic stem-cell research."
"Several polls have shown a clear majority of Americans support the research, which would use embryos that already exist in fertility clinics and would otherwise be thrown out."
"The cells would be used to try and cure conditions like diabetes, spinal cord injuries, Parkinson's and Alzheimer's diseases." 07-06
- Fruit and Vegetables May Protect From Memory Losses (MSNBC News)
"Purple fruits and vegetables, such as blueberries, cranberries and Concord grapes, may be especially beneficial for the brain, says Joseph. In a study on aging mice genetically engineered to develop Alzheimer's, Joseph was able to improve their cognitive function by feeding the animals a diet high in blueberries." 11-06
- Fuller, Dr. Solomon Carter (Time Magazine)
"He wrote that the cases supported Alzheimer's discovery of a particular form of dementia and that it was not due to senility, but rather an actual disease. The research proved to be a watershed in the study of the disorder and Fuller's name was forever linked with modern understanding of the ailment [Alzheimer's Disease]." 02-07
- -09-19-07 New Source for Stem Cells (CBS News)
"Researchers hope to one day extract stem cells from testicles that could be directed to grow into all kinds of tissues to repair everything from a damaged heart to brains destroyed by Alzheimer's to insulin-producing cells to cure diabetes."
"So far, the researchers have found a way to grow different tissues from stem cells isolated from the testes of laboratory mice, but they believe the same technology could work in humans." 09-07
- -06-12-08 Bright Lights Hold Off Dementia (Time.com)
"When it comes to Alzheimer's disease, no one yet knows the best way to halt the gradual slips in memory and other brain functions that are the hallmarks of the disease. But researchers in the Netherlands have found that a simple nonmedical intervention may be just as effective as drugs to keep elderly patients sharp." 06-08
- -Prevention of Major Medical Problems With Diet (Fisher)
Provides recommendations to combat osteoporosis, cancer, heart disease, and Alzheimer's Disease with diet. 9-05
- Medical Literature Guide for Professionals (AMEDEO)
Provides individualized selection of medical journals for keeping up with a topic, such as Parkinson's Disease or Alzheimer's. Includes individualized emails with links to abstracts. Sometimes visitors misspell as Altzheimer's.
- Neurotrophic Factors (Brain Briefing)
Provides information on the factors associated with the regrowth of nerve tissue, an area of research related to Lou Gehrig's Disease (Amyotrophic lateral sclerosis), Alzheimer's Disease, Parkinson's Disease, and other neurological afflictions often associated with aging processes. 6-99
- Health News and Resources for Seniors (Health and Age)
Provides health news (from Reuters) and consumer information on topics such as Alzheimer's Disease, depression, heart disease, impaired mobility, diabetes, and more.
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[Dr. Jerry Adams at jadams@awesomelibrary.org.]
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