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- Protein p25 Associated with Alzheimer's Disease -- and Creativity (HHMI.org)
- " Researchers have found evidence that may partially exonerate a protein known to be a culprit in the progression of Alzheimer's disease. Their new studies show that the protein p25, which wreaks havoc in the brains of patients with Alzheimer's disease, also has a good side in promoting the plasticity of the brain."
- -12-08-05 Protein p25 Associated with Alzheimer's Disease -- and Creativity (HHMI.org)
- " Researchers have found evidence that may partially exonerate a protein known to be a culprit in the progression of Alzheimer's disease. Their new studies show that the protein p25, which wreaks havoc in the brains of patients with Alzheimer's disease, also has a good side in promoting the plasticity of the brain." 12-05.
- -12-11-05 Compound in Some Foods Attack Alzheimer's Agent (Scientific American)
- " 'Resveratrol is a natural polyphenol occurring in abundance in several plants, including grapes, berries and peanuts,' says author Philippe Marambaud of the Litwin-Zucker Research Center for the Study of Alzheimer's Disease and Memory Disorders in Manhasset, N.Y. 'The polyphenol is found in high concentrations in red wines.' "
"The scientists found that 40 micromoles (a measure of the amount of resveratrol in a liter of solution) cut levels of the Alzheimer's-associated molecules--amyloid-beta peptides--by more than half." 9-03 - Alzheimer's Disease - Memory Loss in Mice Reversed (Scientific American)
- More than four million Americans currently suffer from Alzheimer's disease and the number is expected to balloon as the population ages. The results of a new mouse study offer fresh hope that the damage inflicted by the disease could be at least partially reversible."
"In humans, two different substances that accumulate in the brain are implicated in Alzheimer's: twisted neurofibrillary tangles, which include tau proteins, and amyloid deposits comprised of toxic plaque build-up. For the study mice, after the mutant tau gene was dampened and some memory regained, their neuron numbers stabilized but the tangles remained. The tangles themselves may therefore not be responsible for causing memory problems, at least in mice." 7-05 - 01-14-07 Gene Linked to Alzheimer's Disease (MSNBC New)
- "A huge international study has identified a gene that apparently can raise the risk of developing the most common form of Alzheimer's disease, a discovery that may help scientists develop new treatments." 01-07
- Alzheimer's Rate Increases (CBS News)
- "More than 5 million Americans are living with Alzheimer's disease, a 10 percent increase since the last Alzheimer's Association estimate five years ago — and a count that supports the long-forecast dementia epidemic as the population grays." 03-07
- Can Alzheimer's Be Prevented? (Time.com)
- "Few things are as terrifying as losing one's mind. Alzheimer's disease is the most common form of dementia among the elderly and affects as many as 4.5 million Americans, according to the U.S. National Institutes of Health. It currently has no cure. But recent research offers groundbreaking insight into what causes the disease, and how researchers could reduce people's risk." 05-08
- -06-23-08 New Clue to the Cause of Alzheimer's Disease (Time.com)
- "Now, researchers have caused Alzheimer's symptoms in rats by injecting them with one particular form of beta-amyloid. Injections with other forms of beta-amyloid did not cause illness, which may explain why some people have beta-amyloid plaque in their brains but do not show disease symptoms." 06-08
- -07-28-08 Statins May Reduce Risk of Alzheimer's Disease (Newsweek)
- "A study appearing Monday in the journal Neurology found that statins dramatically reduced the risk of developing dementia and Alzheimer's disease among a group of subjects 60 years and older. 'It suggests that if you took statins before dementia set in, you might be 50% less likely to develop the condition,' says Mary Haan, an epidemiology professor at the University of Michigan and the study's lead author. 'That's a really big effect.' " 07-08
- -07-29-08 Study: Pre-Alzheimer's Hits Males Hard (MSNBC News)
- "A milder type of mental decline that often precedes Alzheimer’s disease is alarmingly more common than has been believed, and in men more than women, doctors reported Monday."
"Dr. Ralph Nixon, a New York University psychiatrist and scientific adviser to the Alzheimer’s Association, was blunt."
" 'We’re facing a crisis,' he said."
" 'There are no treatments now to prevent this mental slide or reverse it once it starts.' 07-08 - 07-29-08 New Alzheimer's Drug Shows Promise (CBS News)
- "For the first time, an experimental drug shows promise for halting the progression of Alzheimer's disease by taking a new approach: breaking up the protein tangles that clog victims' brains."
"The encouraging results from the drug called Rember, reported Tuesday at a medical conference in Chicago, electrified a field battered by recent setbacks. The drug was developed by Singapore-based TauRx Therapeutics." 07-08 - -New Test to Predict Alzheimer's Disease (Time.com)
- "Researchers at the University of California, San Francisco (UCSF), and the University of Pittsburgh have developed the first screening tool that can help predict whether elderly patients are at low, moderate or high risk of developing dementia. The new test takes into account characteristic risk factors for dementia, including advanced age and the presence of genes associated with Alzheimer's, but also relies on lesser-known contributors such as patients' body weight and alcohol-drinking habits." 05-09
- -Twenty Percent Fewer May Get Alzheimer's (MSNBC News)
- "Scientists have found three new major genetic links to Alzheimer's, affecting up to 20 percent of people with the brain-wasting disease, and said on Sunday it was the most significant such discovery in 15 years." 09-09
- How to Protect Against Alzheimer's Disease (U.S. News)
- "We all want to dodge the Alzheimer's bullet. And lucky us, Mother Nature has counterbalanced the power of our hard-wired genes by allowing multiple lifestyle choices to greatly influence our aging. Read: Your destiny is not fated; you do have some control." 09-09
- -Reducing the Risk of Alzheimer's Disease with Diet (CBS News)
- "Want to reduce your risk of Alzheimer's disease by some 40 percent?" 04-10
- Study: Effective Test for Alzheimer's Disease Found (New York Times)
- "Researchers report that a spinal fluid test can be 100 percent accurate in identifying patients with significant memory loss who are on their way to developing Alzheimer’s disease." 08-10
- -No Compelling Evidence for Prevention or Treatment of Alzheimer's Disease (New York Times)
- "The scene was a kind of science court. On trial was the question 'Can anything — running on a treadmill, eating more spinach, learning Arabic — prevent Alzheimer’s disease or delay its progression?' "
"To try to answer that question, the National Institutes of Health sponsored the court, appointing a jury of 15 medical scientists with no vested interests in Alzheimer’s research. They would hear the evidence and reach a judgment on what the data showed."
" 'Currently,' the panel wrote, 'no evidence of even moderate scientific quality exists to support the association of any modifiable factor (such as nutritional supplements, herbal preparations, dietary factors, prescription or nonprescription drugs, social or economic factors, medical conditions, toxins or environmental exposures) with reduced risk of Alzheimer’s disease.' "
"To its great surprise, the Duke group discovered a vast amount of literature on Alzheimer’s prevention. Instead of coming up empty on many topics, Dr. Williams said, 'We came up empty on very few.' ”
"The problem, the group wrote, was that 'the quality of the evidence was typically low.' ”
"Low confidence did not necessarily mean the measures did not work — it meant the evidence was so faulty that there was no way of deciding." 08-10 - -04-04-11 Vast New Alzheimer's Disease Research Study (New York Times)
- "The two largest studies of Alzheimer’s disease have led to the discovery of no fewer than five genes that provide intriguing new clues to why the disease strikes and how it progresses."
- New Guide for Diagnosis of Alzheimer's Disease (New York Times)
- "The first new guidelines for diagnosing Alzheimer's disease in nearly 30 years establish earlier stages of the mind-robbing disease, paving the way for spotting and possibly treating the tell-tale signs of dementia much sooner than they are now." 04-11
- New Brain Scan for Diagnosis of Early Alzheimer's (Time.com)
- "Alzheimer’s disease has always been difficult to diagnose — the only way to identify it definitively is by autopsying the brain after death — but scientists may now have an easier way to spot the degenerative brain disease long before that, even before symptoms appear, using brain scans." 12-11