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NewsPapers
- -02-06-06 Study: Up to 79% of Late-Onset Alzheimer's is Genetic (USA Today)
"Genes account for 58% to 79% of a person's risk of developing late-onset Alzheimer's, a study reports today. It's the largest genetic study of Alzheimer's ever." 02-06
- -06-23-08 New Clue to the Cause of Alzheimer's Disease (Time.com)
"Now, researchers have caused Alzheimer's symptoms in rats by injecting them with one particular form of beta-amyloid. Injections with other forms of beta-amyloid did not cause illness, which may explain why some people have beta-amyloid plaque in their brains but do not show disease symptoms." 06-08
Research
- -Study: Early Signs of Alzheimer's Disease Found (BBC - EIN News)
"Scientists have assembled a 'timeline' of the unseen progress of Alzheimer's before symptoms appear."
"It's likely that any new treatment for Alzheimer's would need to be given early to have the best chance of success."
"The ability to detect the very earliest stages of Alzheimer's would not only allow people to plan and access care and existing treatments far sooner, but would also enable new drugs to be trialled in the right people, at the right time." 07-12
- Alzheimer's Disease - Research on Alzheimer's Disease and Diet (Fisher)
Provides recommendations to combat Alzheimer's Disease through diet.
- Brain Implant Improves Thinking in Monkeys (New York Times)
"Scientists have designed a brain implant that sharpened decision making and restored lost mental capacity in monkeys, providing the first demonstration in primates of the sort of brain prosthesis that could eventually help people with damage from dementia, strokes or other brain injuries."
"The device, though years away from commercial development, gives researchers a model for how to support and enhance fairly advanced mental skills in the frontal cortex of the brain, the seat of thinking and planning." 09-12
- New Test for Alzheimer's Disease (CBS News)
"A new test may help scientists answer a perplexing 'which came first' question about the development of Alzheimer's disease, possibly pointing the way to earlier diagnosis or even treatment."
" 'The paper describes an extremely interesting and potentially important advance,' said Dr. Samuel Gandy of Thomas Jefferson University in Philadelphia said. 'This method is light-years ahead of any existing technology for approaching the issue,' said Gandy, who was not part of the research team." 06-06
- Alzheimer's Disease - Memory Loss in Mice Reversed (Scientific American)
More than four million Americans currently suffer from Alzheimer's disease and the number is expected to balloon as the population ages. The results of a new mouse study offer fresh hope that the damage inflicted by the disease could be at least partially reversible."
"In humans, two different substances that accumulate in the brain are implicated in Alzheimer's: twisted neurofibrillary tangles, which include tau proteins, and amyloid deposits comprised of toxic plaque build-up. For the study mice, after the mutant tau gene was dampened and some memory regained, their neuron numbers stabilized but the tangles remained. The tangles themselves may therefore not be responsible for causing memory problems, at least in mice." 7-05
- Alzheimer's Disease Research (Alzheimer Research Forum)
Provides news on Alzheimer's Disease. 7-04
- Alzheimer's Disease Research (National Center for Biotechnology Information)
Provides a summary of gene research related to preventing Alzhimer's disease. "Recently, use of a mouse model of the disease identified an enzyme that may be responsible for the increase in amyloid production characteristic of AD. If a way to regulate this enzyme could be found, then AD may be slowed or halted in some people." 2-02
- Cure for Early Alzheimer's in Mice (Scientific American)
"Alzheimer's disease is characterized by two separate brain lesions: plaques and tangles. The results of a new mouse study indicate that an experimental immune therapy that targets the former can also impact the latter, so long as the disease has not progressed to an advanced state." 8-04
- Curry Spice May Be Helpful for Combating Alzheimer's (WorldHealth.net)
"One of the most promising natural therapies is curcumin, a spice compound extracted from the rootstalks of the turmeric plant and gives curry its yellow color and pungent flavor. While a number of hurdles in converting curcumin into a viable Alzheimer’s therapy must be addressed, the cellular mechanisms by which it beneficially alters the inflammatory processes are being elucidated today." 09-12
- Gut Microbiome Alterations in Alzheimer's Disease (Alzheimer Research Forum)
Alterations in the composition of this complex ecosystem have been associated with the development of a variety of gastrointestinal and metabolic diseases including inflammatory bowel disease (IBD), obesity, diabetes, and insulin resistance10. More recently, the influence of gut microbiota on central nervous system function – often referred to as the gut-brain axis – has received significant attention, and alterations in the gut microbiome have been associated with neurological conditions including autism spectrum disorder, multiple sclerosis, and Parkinson’s disease11–13."
With respect to dementia, a recent study in cognitively impaired elderly participants investigated a limited number of pro- and anti-inflammatory gut bacterial taxa and found altered abundance in individuals with positive amyloid positron emission tomography (PET) imaging14. In addition, recent studies in transgenic mouse models of AD have demonstrated that manipulating gut microbiota can influence cerebral amyloid deposition15,16. However, to date there have been no comprehensive surveys of whole gut microbiota in humans with AD. In this study, we performed bacterial 16S ribosomal RNA (rRNA) gene sequencing of DNA isolated from fecal samples in order to characterize the gut microbial communities in individuals with and without a clinical diagnosis of dementia due to AD. In addition, we examined the relationship between gut microbiota and AD pathology as measured by cerebrospinal fluid (CSF) biomarkers of AD." 06-24-2019
- Study: Risk Factors for Alzheimer's Disease (Time.com)
"Two-thirds of Alzheimer’s cases could be attributed to nine risk factors that are potentially fixable, according to a new study released Thursday." 08-15
- Vast New Alzheimer's Disease Research Study (New York Times)
"The two largest studies of Alzheimer’s disease have led to the discovery of no fewer than five genes that provide intriguing new clues to why the disease strikes and how it progresses."
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