News -02-06-06 Study: Up to 79% of Late-Onset Alzheimer's is Genetic (USA Today) "Genes account for 58% to 79% of a person's risk of developing late-onset Alzheimer's, a study reports today. It's the largest genetic study of Alzheimer's ever." 02-06 -06-23-08 New Clue to the Cause of Alzheimer's Disease (Time.com) "Now, researchers have caused Alzheimer's symptoms in rats by injecting them with one particular form of beta-amyloid. Injections with other forms of beta-amyloid did not cause illness, which may explain why some people have beta-amyloid plaque in their brains but do not show disease symptoms." 06-08 Papers Alzheimer's Disease - Research on Alzheimer's Disease and Diet (Fisher) Provides recommendations to combat Alzheimer's Disease through diet. New Test for Alzheimer's Disease (CBS News) "A new test may help scientists answer a perplexing 'which came first' question about the development of Alzheimer's disease, possibly pointing the way to earlier diagnosis or even treatment." " 'The paper describes an extremely interesting and potentially important advance,' said Dr. Samuel Gandy of Thomas Jefferson University in Philadelphia said. 'This method is light-years ahead of any existing technology for approaching the issue,' said Gandy, who was not part of the research team." 06-06 Research Alzheimer's Disease - Memory Loss in Mice Reversed (Scientific American) More than four million Americans currently suffer from Alzheimer's disease and the number is expected to balloon as the population ages. The results of a new mouse study offer fresh hope that the damage inflicted by the disease could be at least partially reversible." "In humans, two different substances that accumulate in the brain are implicated in Alzheimer's: twisted neurofibrillary tangles, which include tau proteins, and amyloid deposits comprised of toxic plaque build-up. For the study mice, after the mutant tau gene was dampened and some memory regained, their neuron numbers stabilized but the tangles remained. The tangles themselves may therefore not be responsible for causing memory problems, at least in mice." 7-05 Alzheimer's Disease Research (Alzheimer Research Forum) Provides news on Alzheimer's Disease. 7-04 Alzheimer's Disease Research (National Center for Biotechnology Information) Provides a summary of gene research related to preventing Alzhimer's disease. "Recently, use of a mouse model of the disease identified an enzyme that may be responsible for the increase in amyloid production characteristic of AD. If a way to regulate this enzyme could be found, then AD may be slowed or halted in some people." 2-02 Cure for Early Alzheimer's in Mice (Scientific American) "Alzheimer's disease is characterized by two separate brain lesions: plaques and tangles. The results of a new mouse study indicate that an experimental immune therapy that targets the former can also impact the latter, so long as the disease has not progressed to an advanced state." 8-04 Vast New Alzheimer's Disease Research Study (New York Times) "The two largest studies of Alzheimer’s disease have led to the discovery of no fewer than five genes that provide intriguing new clues to why the disease strikes and how it progresses."

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